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4528
Ono Pharmaceutical Co., Ltd. – TYO
Weekly Share Price & Valuation Overview
Market Overview
Open
1641.0000
Close
1686.5000
High
1695.0000
Low
1641.0000
Trend
0.27996

Ono Pharmaceutical Co., Ltd.

Japan • TYO - Tokyo Stock Exchange • 4528 • Currency: JPY

Ono Pharmaceutical Co., Ltd. engages in production, purchase, and sale of pharmaceuticals and diagnostic reagents worldwide. It offers Opdivo Intravenous Infusion and Kyprolis Intravenous Injection for malignant tumors; Emend capsules intravenous injections for chemotherapy-induced nausea and vomiting; Demser capsules for the symptoms in patients with pheochromocytoma; Mektovi, Velexbru, and Braftovi capsules for malignant tumors; and ADLUMIZ tablets for cancer cachexia. It also provides Glactiv tablets for type 2 diabetes; Forxiga tablets for diabetes, chronic heart failure, and chronic kidney disease; Onoact Intravenous Infusion for tachyarrhythmia; Opalmon tablets to treat peripheral circulatory disorder; Coralan for chronic heart failure; Orencia injections for rheumatoid arthritis; Rivastach patches for Alzheimer's disease; Ongentys tablets for Parkinson's disease; Parsabiv, for the treatment of Secondary Hyperparathyroidism; Staybla tablets for overactive bladder; Onon capsules and Dry Syrups for bronchial asthma and allergic rhinitis; and JOYCLU intra-articular injection for the improvement of joint function, as well as Recalbon tablets for osteoporosis. In addition, it develops products for hepatocellular and urothelial carcinoma; ovarian, bladder, prostate, pancreatic, gastric, esophageal, colorectal, thyroid, cell lung, and breast cancer; acute myeloid leukemia; solid tumors; myelodysplastic syndrome; melanoma; T-cell lymphoma; tachyarrhythmia; pemphigus; scleroderma; seizures; diabetic polyneuropathy; neurodegenerative diseases; autoimmune diseases; narcolepsy; and thrombosis. The company has a collaboration with Adimab, LLC to discover novel antibody drugs; Turbine Ltd. to identify and validate novel oncology targets; Harvard University for validating novel therapeutic targets; and a strategic drug discovery collaboration with Sibylla Biotech in central nervous system disorders. The company was founded in 1717 and is headquartered in Osaka, Japan.

Key strengths
  • Healthy operating margin (≥15%) indicates efficient core operations.
  • High gross margin (≥35%) suggests strong pricing power or cost control.
  • Quick ratio ≥1.0 indicates obligations can be met without inventory.
  • Net cash balance sheet provides flexibility for downturns and investment.
Scale & Structure Core size and share structure. TTM values unless noted. “Estimated” where reconciled from per-share × shares.
Market Cap Total equity value of the company (share price × shares outstanding).
JPY 802.61B
Enterprise Value Operating value: market cap + total debt − cash.
JPY 807.27B
Total Revenue (TTM) Sales over the last twelve months. May be estimated from revenue per share when inconsistent.
JPY 496.73B
Gross Profit (TTM) Revenue minus cost of goods sold over the last twelve months. Hidden for financial institutions or if redundant.
JPY 341.44B
EBITDA (TTM) Earnings before interest, taxes, depreciation and amortization (TTM). Hidden for financials or if implausible.
JPY 86.19B
Revenue per Share (TTM) Total revenue divided by shares outstanding (may be estimated).
JPY 1.06K
EPS (TTM) Earnings per share over the last twelve months (may be estimated from net income ÷ shares).
106.44
Dividend Yield Annual dividend ÷ share price. Reconciled using dividend per share when available.
4.68%
Shares Outstanding
469.77M
Float Shares
389.31M
Implied Shares Outstanding
469.77M
Profitability & Efficiency TTM basis. “Reconciled” = numerator ÷ TTM revenue. Margins reflect latest TTM calculations.
Operating Margin (TTM) Strong Operating income ÷ revenue over the last twelve months (reconciled when possible).
17.25%
EBITDA Margin (TTM) Reconciled EBITDA ÷ revenue over the last twelve months (suppressed if EBITDA implausible/financials).
17.35%
Gross Margin (TTM) Reconciled Strong Gross profit ÷ revenue over the last twelve months (reconciled when possible).
68.74%
Profit Margin (TTM) Net income ÷ revenue over the last twelve months (reconciled when possible).
8.64%
Growth Growth rates are YoY unless labeled QoQ.
Revenue Growth Year-over-year revenue growth.
8.40%
Earnings Growth (YoY) Year-over-year earnings growth.
-28.80%
Earnings Growth (QoQ) Quarter-over-quarter earnings growth.
-28.70%
Liquidity & Solvency Balance-sheet health. Debt metrics shown as latest ratios; D/E is a ratio (not %).
Quick Ratio Adequate Liquid current assets ÷ current liabilities (ex-inventory).
2.18
Debt to Equity Total debt ÷ shareholder equity; leverage.
0.18
Total Cash Cash and equivalents.
JPY 139.16B
Total Debt Short + long-term interest-bearing debt.
JPY 138.11B
Net Debt Net Cash Total debt − cash (negative = net cash).
JPY -1.05B
Debt / EBITDA Leverage relative to operating earnings; lower is safer.
1.60
Cash Flow Shown only when internally consistent; margins are TTM.
Operating Cash Flow (TTM) Cash generated by core operations (pre-capex).
JPY 85.02B
OCF Margin (TTM) Operating cash flow ÷ revenue (TTM).
17.12%
Cash Conversion (OpCF/EBITDA)
0.99
Sharemaestro House View
Confidence: 1 Sharemaestro internal conviction (0–3, higher is better). Risk: 3 Sharemaestro internal risk profile (0–3, higher is safer). Operational: 3 Operational quality/consistency (0–3, higher is better). Composite Score: 2 Overall internal composite (0–3, higher is better). Suggested Allocation: 3.33% Indicative portfolio weighting suggestion based on house view.
Structural Insights (experimental)
Ownership & Liquidity
Free Float Proportion of shares available for public trading. 82.9%
Insiders Shares held by company insiders (officers, directors). 14.3%
Institutions Shares held by institutions (funds, pensions). 35.9%
Capital Structure
Potential Dilution Increase in share count if options/convertibles exercise.
None detected
Net Debt Total debt − cash (negative = net cash).
JPY -1.05B
-0.2% of revenue Net debt relative to revenue — debt load vs business scale.
Resilience Score 0–100 composite of liquidity, leverage and cash conversion; higher is better. If inputs are unavailable, we estimate using proxies (Net debt vs revenue, Cash-to-Debt). It is a guide, not a rating. 86
Methodology Notes
  • Margins shown on a TTM basis. “Reconciled” = numerator ÷ TTM revenue for internal consistency.
  • Cash Flow section is displayed only when figures are self-consistent (and hidden for financials).
As of: 2025-08-18 10:03

Disclaimer: Information is compiled from publicly available sources and is subject to errors and omissions. It is provided as a guide only and does not constitute investment advice. Please do your own research.

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