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4503
Astellas Pharma Inc. – TYO
Weekly Share Price & Valuation Overview
Market Overview
Open
1562.5000
Close
1580.5000
High
1583.0000
Low
1549.0000
Trend
0.32643

Astellas Pharma Inc.

Japan • TYO - Tokyo Stock Exchange • 4503 • Currency: JPY

Astellas Pharma Inc. manufactures, markets, and imports and exports pharmaceuticals in Japan and internationally. The company provides XTANDI, a treatment for prostate cancer; XOSPATA, a treatment for acute myeloid leukemia (AML); VYLOY, a treatment for gastric cancer; and PADCEV, a treatment for patients with metastatic urothelial cancer. It also offers VEOZAH, a treatment for vasomotor symptoms due to menopause; IZERVAY, a treatment for geographic atrophy (GA) secondary to age-related macular degeneration (AMD); EVRENZO, a treatment for anemia associated with chronic kidney disease (CKD); Betanis/Myrabetriq/BETMIGA, a treatment for overactive bladder; and Prograf, an immunosuppressants. The company has a research collaboration with xFOREST Therapeutics to develop RNA-targeted therapies and a partnership agreement with Roche Diabetes Care Japan Co., Ltd. to develop and commercialize integrated diabetes self-management solution. Astellas Pharma Inc. was formerly known as Yamanouchi Pharmaceutical Co. Ltd. and changed its name to Astellas Pharma Inc. in April 2005. The company was founded in 1923 and is headquartered in Chuo, Japan.

Key strengths
  • Healthy operating margin (≥15%) indicates efficient core operations.
  • High gross margin (≥35%) suggests strong pricing power or cost control.
  • Earnings growth ≥10% supports improving profitability trajectory.
Scale & Structure Core size and share structure. TTM values unless noted. “Estimated” where reconciled from per-share × shares.
Market Cap Total equity value of the company (share price × shares outstanding).
JPY 2.99T
Enterprise Value Operating value: market cap + total debt − cash.
JPY 3.67T
Total Revenue (TTM) Sales over the last twelve months. May be estimated from revenue per share when inconsistent.
JPY 1.94T
Gross Profit (TTM) Revenue minus cost of goods sold over the last twelve months. Hidden for financial institutions or if redundant.
JPY 1.59T
EBITDA (TTM) Earnings before interest, taxes, depreciation and amortization (TTM). Hidden for financials or if implausible.
JPY 485.44B
Revenue per Share (TTM) Total revenue divided by shares outstanding (may be estimated).
JPY 1.09K
EPS (TTM) Earnings per share over the last twelve months (may be estimated from net income ÷ shares).
28.24
Dividend Yield Annual dividend ÷ share price. Reconciled using dividend per share when available.
4.67%
Shares Outstanding
1.79B
Float Shares
1.75B
Implied Shares Outstanding
1.79B
Profitability & Efficiency TTM basis. “Reconciled” = numerator ÷ TTM revenue. Margins reflect latest TTM calculations.
Operating Margin (TTM) Strong Operating income ÷ revenue over the last twelve months (reconciled when possible).
20.57%
EBITDA Margin (TTM) Reconciled EBITDA ÷ revenue over the last twelve months (suppressed if EBITDA implausible/financials).
24.96%
Gross Margin (TTM) Reconciled Strong Gross profit ÷ revenue over the last twelve months (reconciled when possible).
81.86%
Profit Margin (TTM) Net income ÷ revenue over the last twelve months (reconciled when possible).
4.19%
ROA Return on assets: net income ÷ total assets.
5.10%
ROE Return on equity: net income ÷ shareholder equity.
5.17%
Growth Growth rates are YoY unless labeled QoQ.
Revenue Growth Year-over-year revenue growth.
6.90%
Earnings Growth (YoY) Strong Year-over-year earnings growth.
82.00%
Earnings Growth (QoQ) Quarter-over-quarter earnings growth.
82.00%
Liquidity & Solvency Balance-sheet health. Debt metrics shown as latest ratios; D/E is a ratio (not %).
Quick Ratio Liquid current assets ÷ current liabilities (ex-inventory).
0.81
Debt to Equity Total debt ÷ shareholder equity; leverage.
0.60
Total Cash Cash and equivalents.
JPY 215.40B
Total Debt Short + long-term interest-bearing debt.
JPY 889.49B
Net Debt Total debt − cash (negative = net cash).
JPY 674.09B
Debt / EBITDA Leverage relative to operating earnings; lower is safer.
1.83
Cash Flow Shown only when internally consistent; margins are TTM.
Operating Cash Flow (TTM) Cash generated by core operations (pre-capex).
JPY 236.75B
Free Cash Flow (TTM) Cash after capex; funds buybacks, dividends, and debt paydown.
JPY 129.92B
OCF Margin (TTM) Operating cash flow ÷ revenue (TTM).
12.17%
FCF Margin (TTM) Free cash flow ÷ revenue (TTM).
6.68%
Cash Conversion (OpCF/EBITDA)
0.49
Sharemaestro House View
Confidence: 2 Sharemaestro internal conviction (0–3, higher is better). Risk: 2 Sharemaestro internal risk profile (0–3, higher is safer). Operational: 2 Operational quality/consistency (0–3, higher is better). Composite Score: 3 Overall internal composite (0–3, higher is better). Suggested Allocation: 5.00% Indicative portfolio weighting suggestion based on house view.
Structural Insights (experimental)
Ownership & Liquidity
Free Float Proportion of shares available for public trading. 97.5%
Insiders Shares held by company insiders (officers, directors). 0.2%
Institutions Shares held by institutions (funds, pensions). 51.5%
Capital Structure
Potential Dilution Increase in share count if options/convertibles exercise.
0.2%
Net Debt Total debt − cash (negative = net cash).
JPY 674.09B
34.7% of revenue Net debt relative to revenue — debt load vs business scale.
Resilience Score 0–100 composite of liquidity, leverage and cash conversion; higher is better. If inputs are unavailable, we estimate using proxies (Net debt vs revenue, Cash-to-Debt). It is a guide, not a rating. 34
Methodology Notes
  • Margins shown on a TTM basis. “Reconciled” = numerator ÷ TTM revenue for internal consistency.
  • Cash Flow section is displayed only when figures are self-consistent (and hidden for financials).
As of: 2025-08-18 10:03

Disclaimer: Information is compiled from publicly available sources and is subject to errors and omissions. It is provided as a guide only and does not constitute investment advice. Please do your own research.

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